Call for proposals to develop advanced Virtual Human Twins (VHTs).

About this grant

Call for proposals to develop advanced Virtual Human Twins (VHTs). With a total budget of €35.00 million, this initiative aims to create dynamic, multiscale digital representations of individuals to better understand cancer onset and progression. These in-silico models are intended to revolutionize personalized medicine by allowing clinicians to simulate and select the most effective intervention options at various anatomical levels, from cellular molecular profiles to entire organ systems. The Commission expects to fund approximately four projects, with individual awards ranging between €8.00 and €9.00 million. Key activities include: Multiscale Modeling: Developing VHTs that integrate FAIR (Findable, Accessible, Interoperable, Reusable) data, including multi-omics, medical imaging, and real-world clinical data, while utilizing AR/VR for model visualization; Validation & Clinical Uptake: Updating and validating these models with longitudinal patient data to demonstrate their usability and capacity to deliver clinically meaningful observations in real-world treatment settings; Open Science & Infrastructure: Making all data and model assets available through the UNCAN.eu and the Advanced VHT Platform. Newly collected datasets must be recorded in the European Health Data Space (EHDS) catalogue; and Multidisciplinary Collaboration: Ensuring active cooperation between AI experts, healthcare professionals, and patients throughout the development process to ensure the models reflect human diversity, including age, sex, and gender.

How to apply

1. 1Verify eligibility criteria, including applicant type (e.g., SMEs, consortia), geographic requirements, and funding rates (often 40-100% co-financing).
2. 2Form a consortium if required (e.g., minimum partners from multiple countries for collaborative projects).
3. 3Register as a user and your organization on the EU Funding & Tenders Portal to obtain a Participant Identification Code (PIC).
4. 4Download templates, prepare Part A (administrative data) and Part B (technical description, budget, impact), and run validation checks.
5. 5Submit online before the deadline; track via confirmation email and code, with evaluation taking 3-6 months.
6. 6Visit https://eufundingportal.eu for application details

Application tips