Intramural - Extramural Collaboration for Advanced 3-D Tissue Models for Drug Screening (Clinical Trial Not Allowed)

About this grant

NIH intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications that will develop, validate and demonstrate the utility of advanced 3-D tissue models for testing the efficacy of various therapeutic modalities, including small molecules and biologics and accelerate the discovery and development of new therapeutics across different diseases. The initiative will develop advanced 3-D drug screening models adaptable to high throughput assays. These non-animal models are expected Grant Number: RFA-TR-25-016. Expected awards: 2.

Eligibility requirements

All of the following criteria must be met:

• Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-Eligible ApplicantsNon-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizati
• Grant Number: RFA-TR-25-016

What the funding covers

• See official listing for award details
• Expected Number of Awards: 2
• Total Program Funding: $16,00,000

How to apply

1. 1Applications must be submitted through grants.gov
2. 2Grant Number: RFA-TR-25-016
3. 3Posted: 2025-09-29

Application tips