Strategic Prevention Framework - Partnerships for Success for Communities/Tribes

About this grant

The purpose of the SPF-PFS-Communities/Tribes program is to help prevent and reduce the initiation and progression of substance use and its related problems by supporting the development and delivery of community-based substance use prevention services that strengthen protective factors, reduce risk factors, build resilience, and promote well-being; and expand and strengthen the capacity of prevention providers serving communities and tribes to implement evidence-based, evidence-informed, and co Grant Number: SP-26-002. Expected awards: 32.

Eligibility requirements

All of the following criteria must be met:

• Eligible applicants are political subdivisions of States; Indian tribes or tribal organizations (as such terms are defined in section 5304 of title 25); health facilities or programs operated by or in accordance with a contract or award with the Indian Health Service; or other public or private non-profit entities, including faith-based organizations.

What the funding covers

• See official listing for award details
• Expected Number of Awards: 32
• Total Program Funding: $8.2M

How to apply

1. 1Check eligibility: Confirm your organization type (e.g., nonprofit, state government), project alignment, and deadlines from the opportunity synopsis.
2. 2Register: Create a Grants.gov account via Login.gov, complete SAM.gov and UEI registration, and authorize organization representatives (takes 2-4 weeks).
3. 3Prepare application: Select "Apply" to open Workspace, download forms (e.g., SF-424), complete offline/online with validation checks, and upload supporting docs like budgets and narratives.
4. 4Submit and track: Check package for errors, sign/submit via Authorized Organization Representative (AOR), and monitor status with your tracking number
5. 5Applications must be submitted through grants.gov
6. 6Grant Number: SP-26-002
7. 7Posted: 2026-03-20

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