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Call for proposals to develop advanced Virtual Human Twins (VHTs).

European Union

Call for proposals to develop advanced Virtual Human Twins (VHTs). With a total budget of €35.00 million, this initiative aims to create dynamic, multiscale digital representations of individuals to better understand cancer onset and progression. These in-silico models are intended to revolutionize personalized medicine by allowing clinicians to simulate and select the most effective intervention options at various anatomical levels, from cellular molecular profiles to entire organ systems. The Commission expects to fund approximately four projects, with individual awards ranging between €8.00 and €9.00 million. Key activities include: Multiscale Modeling: Developing VHTs that integrate FAIR (Findable, Accessible, Interoperable, Reusable) data, including multi-omics, medical imaging, and real-world clinical data, while utilizing AR/VR for model visualization; Validation & Clinical Uptake: Updating and validating these models with longitudinal patient data to demonstrate their usability and capacity to deliver clinically meaningful observations in real-world treatment settings; Open Science & Infrastructure: Making all data and model assets available through the UNCAN.eu and the Advanced VHT Platform. Newly collected datasets must be recorded in the European Health Data Space (EHDS) catalogue; and Multidisciplinary Collaboration: Ensuring active cooperation between AI experts, healthcare professionals, and patients throughout the development process to ensure the models reflect human diversity, including age, sex, and gender.

Call for proposals to address the dual challenge of the healthcare sector’s environmental footprint and its vulnerability to climate change.

European Union

Call for proposals to address the dual challenge of the healthcare sector’s environmental footprint and its vulnerability to climate change. With a total budget of €45.00 million, this initiative seeks to develop and pilot inclusive, accessible interventions that reduce health vulnerabilities while simultaneously greening healthcare operations. As the health sector is responsible for nearly 5% of global greenhouse gas emissions, this call prioritizes the development of low-carbon medical technologies and evidence-based frameworks to quantify the health co-benefits of climate mitigation. The Commission intends to award several grants, with individual projects receiving between €7.00 and €8.00 million. Applicants are expected to focus on scalable and transferable solutions that can be applied across diverse regional and socio-economic contexts. Key activities include: Intervention Piloting: Developing tools to address climate-related health outcomes and reducing the vulnerability of healthcare infrastructures and supply chains; Decarbonization Technologies: Creating low-carbon medical devices and digital solutions to minimize the emission of pollutants into air, water, and soil; Methodology Development: Designing harmonized frameworks and metrics to assess the cost-benefit ratio of climate adaptation versus mitigation strategies in the health sector; and Community Preparedness: Exploring the role of primary care and lifestyle practices in increasing the resilience of individuals and local communities to environmental stressors.

Call for proposals to bolster the competitiveness of the EU biotechnology sector by advancing “closer-to-deployment” health innovations.

European Union

Call for proposals to bolster the competitiveness of the EU biotechnology sector by advancing closer-to-deployment health innovations. With a total budget of €29.50 million, this initiative specifically targets the field of regenerative medicine, providing follow-on funding for promising research previously supported by EU R&I actions. The goal is to bridge the gap between early-stage research and market readiness, accelerating the delivery of life-changing therapies to patients. The call seeks to fund high-impact projects with substantial awards to ensure innovations reach clinical or industrial maturity. Award Range: Between €6.00 and €8.00 million per project. To be successful, proposals must demonstrate a clear pathway from previous EU-funded success to future healthcare impact.

Call for proposals to fund research and innovation actions (RIAs) focused on advancing healthcare through digitalization and data exchange January 28, 2026; Horizon Europe funding opportunities ; Health Grants , Innovation grants , Research grants This initiative provides up to €43.

European Union

This initiative provides up to €43.3 million to fund pre-competitive research and innovation focused on novel tools and technologies that improve the prevention, diagnosis, treatment, and management of diseases. The call specifically targets the digital transformation of healthcare by exploiting the full potential of data exchange and digitalisation. Proposals must address an unmet public health need, such as diseases with a high patient burden or significant economic impact. Key focus areas include: Demonstrating how research can be translated into innovative solutions that fit into Europe’s fragmented healthcare systems; Leveraging advanced analytics and artificial intelligence to improve diagnostic accuracy, shorten time-to-market, and provide personalized health interventions; Ensuring that health technologies account for demographic trends and the real-life challenges of patients with complex chronic diseases. Selected projects are expected to contribute to the EU’s Life Sciences Strategy by strengthening the competitiveness of the European health industry and fostering technological leadership.

Call for nominations to endow the prestigious Frontiers of Knowledge Awards, which recognize world-class research and artistic creation of singular impact.

European Union

Call for nominations to endow the prestigious Frontiers of Knowledge Awards, which recognize world-class research and artistic creation of singular impact. Now in their nineteenth edition, these awards honor fundamental advances that expand the boundaries of human knowledge or represent the emergence of new interdisciplinary fields. Each of the eight award categories—spanning Basic Sciences, Biology and Biomedicine, ICT, Climate Change, Economics, Humanities, Social Sciences, and Music and Opera.

Call for proposals to support pre-competitive research and innovation in the health sector.

European Union

€30Mnon-repayable

Call for proposals to support pre-competitive research and innovation in the health sector. This initiative seeks to foster the development of safe, effective, and affordable health innovations that address unmet public health needs, ranging from disease prevention and precision diagnostics to chronic disease management. Projects are expected to contribute to the IHI JU Strategic Research and Innovation Agenda by improving the understanding of health determinants and enhancing the competitiveness of the EU health industry. Furthermore, applicants are encouraged to incorporate digital solutions like AI, consider regulatory strategies for timely implementation, and provide open access to research outputs to benefit the wider healthcare community. The Call offers awards of up to EUR 30,000,000.