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€1M – €10.6Mnon-repayable

Call for proposals to support civil protection and disaster risk management projects.

European Union

With a total budget of EUR 10.6 million, this call provides grants of up to EUR 1 million to strengthen disaster resilience and cooperation both within the Union Civil Protection Mechanism (UCPM) and with third-party partners. Eligible applicants include public or private legal entities, and selected projects are expected to be completed within an initial duration of 24 months. The call is organized around three primary pillars designed to enhance the Preparedness Union Strategy: Priority 1: Risk Awareness: Focuses on fostering a culture of prevention among the general public. This includes fighting disinformation, engaging volunteers, and ensuring that vulnerable groups have access to evidence-based risk information; Priority 2: Early Warning to Early Action: Aims to bridge the gap between forecasting institutions and decision-makers. Projects should improve public warning systems and leverage emerging technologies like Artificial Intelligence to ensure alerts lead to rapid, effective responses; and Priority 3: Institutional Capacity: Seeks to build robust civil protection systems by embedding a preparedness-by-design principle. This involves integrating lessons learned from past emergencies and facilitating the transfer of scientific innovation into operational planning. By funding these initiatives, the Commission intends to overcome the challenges posed by cross-border hazards—such as wildfires, floods, and pandemics—which occur regardless of national boundaries. Successful proposals must demonstrate a clear plan for enhancing interoperability between organizations and sectors, ultimately resulting in a more coordinated and technologically advanced disaster risk management framework across Europe.

Call for proposals to develop next-generation Smart and Multifunctional Textiles (SMT) designed to enhance soldier survivability against modern battlefield threats, specifically drone-based surveillance.

European Union

€20Mnon-repayable

Call for proposals to develop next-generation Smart and Multifunctional Textiles (SMT) designed to enhance soldier survivability against modern battlefield threats, specifically drone-based surveillance. As symmetric warfare returns to Europe, this initiative seeks to move beyond traditional uniforms by integrating innovative materials that can interact with their environment. The project aims to develop individual camouflage solutions that are both static and dynamic, protecting dismounted soldiers from high-precision sensors and unmanned aerial vehicles (UAVs) across diverse climates, including Arctic and tropical zones. A total of EUR 20,000,000 is available, with individual awards potentially covering the full amount. By harmonizing soldier system requirements across EU Member States, this effort aims to: Modernize Operational Capacity: Equip European forces with uniforms that regulate temperature and manage moisture in extreme environments; Foster Innovation: Stimulate the European textile and defense industries to create a fully independent supply chain for smart materials; and Increase Combat Effectiveness: Provide soldiers with a technological edge that allows them to operate undetected during both day and night operations, reducing the Union's strategic dependencies on external defense technologies.

Call for proposals to establish a coordinated European Research Area (ERA) policy action to accelerate the development, validation, and uptake of New Approach Methodologies (NAMs) in biomedical research and regulatory testing.

European Union

€2.9Mnon-repayable

Call for proposals to establish a coordinated European Research Area (ERA) policy action to accelerate the development, validation, and uptake of New Approach Methodologies (NAMs) in biomedical research and regulatory testing. This call provides a total of EUR 2.90 million to fund a single overarching proposal that will harmonize strategies across Member States and Associated Countries for the 2025–2027 period. The project must facilitate an EU-wide forum involving ministries, regulatory agencies, academia, and the pharmaceutical industry. The action is structured around four primary Working Groups (WGs): WG1 (Development & Infrastructure): Identifying priority biological areas and infrastructures to leverage scientific strengths across different regions; WG2 (Validation & Uptake): Defining criteria for regulatory acceptance and prioritizing mature NAMs for qualification by the MedTech and pharmaceutical sectors; WG3 (Education & Training): Mapping and developing high-quality training modules on NAMs and the 3Rs principles (Replacement, Reduction, and Refinement) in partnership with knowledge institutes; WG4 (Openness & Awareness): Promoting open access to protocols and negative research results to prevent unnecessary duplication of animal testing and increasing regulator confidence in non-animal methods.

€9M – €44.2Mnon-repayable

Call for proposals to accelerate the development of vaccine candidates for emerging and re-emerging viral threats.

European Union

Call for proposals to accelerate the development of vaccine candidates for emerging and re-emerging viral threats. With a total budget of EUR 44.20 million, individual grants are expected to range between EUR 9.00 and 11.00 million. This initiative aims to diversify the global R&D portfolio and strengthen the EU’s leadership in pandemic preparedness, particularly as climate change accelerates the risk of viral disease emergence. Applicants must focus their proposal on advancing existing vaccine candidates for one of the following specific viruses: Mammarenaviruses: Junin or Lassa; Hantaviruses: Andes, Hantaan, or Sin Nombre; Other Emerging Viruses: Hendra, Enterovirus D68, or Venezuelan equine encephalitis. Proposals must address: Characterization and In-vivo Testing: Finalizing in-vitro characterization and conducting in-vivo protection tests in animal models (including non-human primates if requested by regulators); GMP Manufacturing: Producing batches of the most promising candidates according to Good Manufacturing Practices (GMP); Clinical Safety: Executing first-in-human clinical safety studies that outline a clear regulatory pathway; as well as Inclusive Research: Analyzing immune response and efficacy with attention to critical factors such as sex, age, disability, and ethnicity. For instance, researchers should note that vaccine responses can vary across ethnic groups; some studies have indicated that certain populations, such as those of African descent, may show different antibody titer levels or adverse event profiles compared to Caucasian populations, necessitating diverse clinical trial recruitment.

Call for proposals to support projects that aim to drive the integration of New Approach Methodologies (NAMs) across the biomedical and chemical safety spectrum.

European Union

€5M – €49Mnon-repayable

Call for proposals to support projects that aim to drive the integration of New Approach Methodologies (NAMs) across the biomedical and chemical safety spectrum. With a total budget of EUR 49.00 million, the call provides grants between EUR 5.00 and 8.00 million to support projects that reduce reliance on animal testing while enhancing the human relevance of drug discovery and regulatory assessments. Proposals should focus on developing or optimizing scalable, reproducible platforms that utilize cutting-edge technologies. These include: Complex In-Vitro Models: Utilizing induced Pluripotent Stem Cells (iPSC), patient-derived organoids, and sophisticated Organ-on-Chip (OoC) systems; Digital Innovation: Incorporating AI-driven predictive modeling and Virtual Twin technology to simulate disease progression and intervention responses; and Real-time Monitoring: Integrating embedded sensors to capture immediate physiological responses.

Call for proposals to establish a coordinated network of Centres of Excellence (CoEs) for Advanced Therapy Medicinal Products (ATMPs).

European Union

€3.9Mnon-repayable

Call for proposals to establish a coordinated network of Centres of Excellence (CoEs) for Advanced Therapy Medicinal Products (ATMPs). With a total budget of EUR 3.90 million, this call seeks to consolidate Europe's scattered innovation hubs into a world-class ecosystem capable of competing globally in the development of gene therapies, cell therapies, and tissue-engineered products. The initiative aims to bridge the gap from laboratory discovery to patient delivery by supporting existing centres embedded within vibrant bioclusters. Selected CoEs must already possess critical infrastructure, including state-of-the-art Good Manufacturing Practice (GMP) facilities and clinical trial capabilities. The network is intended to be limited to a maximum of 10 centres across the EU, each offering complementary expertise to ensure comprehensive coverage of various ATMP technologies. Proposed projects, spanning the period of 2027–2030, must address the following mandates: Policy and Harmonization: Develop recommendations for clinical trials, logistics, and the harmonization of market access and reimbursement procedures; Long-term Vision: Create a roadmap with clear milestones to position Europe as a global leader in ATMP research and innovation by 2035; Stakeholder Engagement: Establish a diverse advisory board and foster a multi-sectoral consortium including regulators, industry actors, and patient organizations; and Education: Design training programs for the next generation of scientists and conduct outreach to improve public understanding of advanced therapies.