Open grants
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491 verified open funding opportunities
Call for proposals to fund collaborative projects that implement Value-Based Healthcare (VBHC) models.
European Union
Call for proposals to fund collaborative projects that implement Value-Based Healthcare (VBHC) models. This initiative is designed to bridge the gap between high-maturity, market-ready medical solutions and their formal adoption into real-world clinical practice. With awards of up to EUR 700,000, the program supports industry-led projects that demonstrate how digital and data-driven care pathways can improve patient outcomes while simultaneously enhancing the economic sustainability of healthcare systems. The funding covers activities for up to 24 months, focusing on the practical deployment of innovations rather than early-stage research. Projects are expected to move beyond technical development to achieve broad clinical validation and market readiness.
Call for proposals to support civil protection and disaster risk management projects.
European Union
With a total budget of EUR 10.6 million, this call provides grants of up to EUR 1 million to strengthen disaster resilience and cooperation both within the Union Civil Protection Mechanism (UCPM) and with third-party partners. Eligible applicants include public or private legal entities, and selected projects are expected to be completed within an initial duration of 24 months. The call is organized around three primary pillars designed to enhance the Preparedness Union Strategy: Priority 1: Risk Awareness: Focuses on fostering a culture of prevention among the general public. This includes fighting disinformation, engaging volunteers, and ensuring that vulnerable groups have access to evidence-based risk information; Priority 2: Early Warning to Early Action: Aims to bridge the gap between forecasting institutions and decision-makers. Projects should improve public warning systems and leverage emerging technologies like Artificial Intelligence to ensure alerts lead to rapid, effective responses; and Priority 3: Institutional Capacity: Seeks to build robust civil protection systems by embedding a preparedness-by-design principle. This involves integrating lessons learned from past emergencies and facilitating the transfer of scientific innovation into operational planning. By funding these initiatives, the Commission intends to overcome the challenges posed by cross-border hazards—such as wildfires, floods, and pandemics—which occur regardless of national boundaries. Successful proposals must demonstrate a clear plan for enhancing interoperability between organizations and sectors, ultimately resulting in a more coordinated and technologically advanced disaster risk management framework across Europe.
Call for proposals to develop next-generation Smart and Multifunctional Textiles (SMT) designed to enhance soldier survivability against modern battlefield threats, specifically drone-based surveillance.
European Union
Call for proposals to develop next-generation Smart and Multifunctional Textiles (SMT) designed to enhance soldier survivability against modern battlefield threats, specifically drone-based surveillance. As symmetric warfare returns to Europe, this initiative seeks to move beyond traditional uniforms by integrating innovative materials that can interact with their environment. The project aims to develop individual camouflage solutions that are both static and dynamic, protecting dismounted soldiers from high-precision sensors and unmanned aerial vehicles (UAVs) across diverse climates, including Arctic and tropical zones. A total of EUR 20,000,000 is available, with individual awards potentially covering the full amount. By harmonizing soldier system requirements across EU Member States, this effort aims to: Modernize Operational Capacity: Equip European forces with uniforms that regulate temperature and manage moisture in extreme environments; Foster Innovation: Stimulate the European textile and defense industries to create a fully independent supply chain for smart materials; and Increase Combat Effectiveness: Provide soldiers with a technological edge that allows them to operate undetected during both day and night operations, reducing the Union's strategic dependencies on external defense technologies.
Call for proposals to establish a coordinated European Research Area (ERA) policy action to accelerate the development, validation, and uptake of New Approach Methodologies (NAMs) in biomedical research and regulatory testing.
European Union
Call for proposals to establish a coordinated European Research Area (ERA) policy action to accelerate the development, validation, and uptake of New Approach Methodologies (NAMs) in biomedical research and regulatory testing. This call provides a total of EUR 2.90 million to fund a single overarching proposal that will harmonize strategies across Member States and Associated Countries for the 2025–2027 period. The project must facilitate an EU-wide forum involving ministries, regulatory agencies, academia, and the pharmaceutical industry. The action is structured around four primary Working Groups (WGs): WG1 (Development & Infrastructure): Identifying priority biological areas and infrastructures to leverage scientific strengths across different regions; WG2 (Validation & Uptake): Defining criteria for regulatory acceptance and prioritizing mature NAMs for qualification by the MedTech and pharmaceutical sectors; WG3 (Education & Training): Mapping and developing high-quality training modules on NAMs and the 3Rs principles (Replacement, Reduction, and Refinement) in partnership with knowledge institutes; WG4 (Openness & Awareness): Promoting open access to protocols and negative research results to prevent unnecessary duplication of animal testing and increasing regulator confidence in non-animal methods.
Call for proposals to accelerate the development of vaccine candidates for emerging and re-emerging viral threats.
European Union
Call for proposals to accelerate the development of vaccine candidates for emerging and re-emerging viral threats. With a total budget of EUR 44.20 million, individual grants are expected to range between EUR 9.00 and 11.00 million. This initiative aims to diversify the global R&D portfolio and strengthen the EU’s leadership in pandemic preparedness, particularly as climate change accelerates the risk of viral disease emergence. Applicants must focus their proposal on advancing existing vaccine candidates for one of the following specific viruses: Mammarenaviruses: Junin or Lassa; Hantaviruses: Andes, Hantaan, or Sin Nombre; Other Emerging Viruses: Hendra, Enterovirus D68, or Venezuelan equine encephalitis. Proposals must address: Characterization and In-vivo Testing: Finalizing in-vitro characterization and conducting in-vivo protection tests in animal models (including non-human primates if requested by regulators); GMP Manufacturing: Producing batches of the most promising candidates according to Good Manufacturing Practices (GMP); Clinical Safety: Executing first-in-human clinical safety studies that outline a clear regulatory pathway; as well as Inclusive Research: Analyzing immune response and efficacy with attention to critical factors such as sex, age, disability, and ethnicity. For instance, researchers should note that vaccine responses can vary across ethnic groups; some studies have indicated that certain populations, such as those of African descent, may show different antibody titer levels or adverse event profiles compared to Caucasian populations, necessitating diverse clinical trial recruitment.
Call for proposals to support projects that aim to drive the integration of New Approach Methodologies (NAMs) across the biomedical and chemical safety spectrum.
European Union
Call for proposals to support projects that aim to drive the integration of New Approach Methodologies (NAMs) across the biomedical and chemical safety spectrum. With a total budget of EUR 49.00 million, the call provides grants between EUR 5.00 and 8.00 million to support projects that reduce reliance on animal testing while enhancing the human relevance of drug discovery and regulatory assessments. Proposals should focus on developing or optimizing scalable, reproducible platforms that utilize cutting-edge technologies. These include: Complex In-Vitro Models: Utilizing induced Pluripotent Stem Cells (iPSC), patient-derived organoids, and sophisticated Organ-on-Chip (OoC) systems; Digital Innovation: Incorporating AI-driven predictive modeling and Virtual Twin technology to simulate disease progression and intervention responses; and Real-time Monitoring: Integrating embedded sensors to capture immediate physiological responses.
Call for proposals to establish a coordinated network of Centres of Excellence (CoEs) for Advanced Therapy Medicinal Products (ATMPs).
European Union
Call for proposals to establish a coordinated network of Centres of Excellence (CoEs) for Advanced Therapy Medicinal Products (ATMPs). With a total budget of EUR 3.90 million, this call seeks to consolidate Europe's scattered innovation hubs into a world-class ecosystem capable of competing globally in the development of gene therapies, cell therapies, and tissue-engineered products. The initiative aims to bridge the gap from laboratory discovery to patient delivery by supporting existing centres embedded within vibrant bioclusters. Selected CoEs must already possess critical infrastructure, including state-of-the-art Good Manufacturing Practice (GMP) facilities and clinical trial capabilities. The network is intended to be limited to a maximum of 10 centres across the EU, each offering complementary expertise to ensure comprehensive coverage of various ATMP technologies. Proposed projects, spanning the period of 2027–2030, must address the following mandates: Policy and Harmonization: Develop recommendations for clinical trials, logistics, and the harmonization of market access and reimbursement procedures; Long-term Vision: Create a roadmap with clear milestones to position Europe as a global leader in ATMP research and innovation by 2035; Stakeholder Engagement: Establish a diverse advisory board and foster a multi-sectoral consortium including regulators, industry actors, and patient organizations; and Education: Design training programs for the next generation of scientists and conduct outreach to improve public understanding of advanced therapies.
Call for proposals to address the significant sex and gender disparities in cardiovascular diseases (CVDs), which accounted for over 1.
European Union
Call for proposals to address the significant sex and gender disparities in cardiovascular diseases (CVDs), which accounted for over 1.7 million deaths (32% of all deaths) in the EU in 2021. With a total budget of EUR 39.30 million, the call offers individual awards between EUR 6.00 and 7.00 million to support projects that translate basic biological discoveries into innovative prevention, diagnosis, and treatment strategies tailored to specific physiological and sociocultural needs. Proposals are expected to further the understanding of structural, hormonal, and biological distinctions between sexes. Key focus areas include: Tailored Risk Models: Developing sex-specific models for better disease detection and prevention; Determinant Identification: Validating health determinants by integrating data from disciplines like molecular biology, genetics, and social epidemiology; Data Integration: Utilizing existing health registries, cohorts, and biobanks while ensuring any new data adheres to FAIR principles; and Technological Innovation: Encouraging the use of advanced tools, including Generative AI, to support research outcomes.
Call for proposals to support projects that aim at mitigating the long-term health and economic impacts of persistent conditions resulting from microbial infections (excluding cancer).
European Union
Call for proposals to support projects that aim at mitigating the long-term health and economic impacts of persistent conditions resulting from microbial infections (excluding cancer). With a total budget of EUR 39.30 million, this initiative seeks to award individual grants between EUR 6.00 and 8.00 million to projects that improve the prevention, diagnosis, and management of these often underdiagnosed conditions. Proposals should adopt a multidisciplinary approach to identify risk and protective factors—such as genetics and inflammatory responses—and increase our understanding of disease pathophysiology. Key research areas include: Developing clinically validated diagnostic tools and biomarkers; Conducting early-stage clinical trials for preventive or therapeutic interventions; Identifying effective rehabilitation strategies, including physical and cognitive therapies; and Integrating disease management into primary and specialized healthcare settings.
Call for proposals to support projects that to address the significant challenge of low-value care, which is estimated to account for up to one-fifth of global healthcare spending.
European Union
Call for proposals to support projects that to address the significant challenge of low-value care, which is estimated to account for up to one-fifth of global healthcare spending. With a total budget of €38 million and individual awards expected around €10 million, the initiative seeks to develop evidence-based methodologies to identify, measure, and reduce wasteful medical practices. By reallocating these resources, the program aims to maximize health outcomes, improve the resilience of care systems, and reduce the environmental footprint of healthcare delivery. Selected projects must adopt a patient-centered, multidisciplinary approach to achieve the following: Identification and Measurement: Develop a deep understanding of how to detect low-value care throughout the healthcare process, including testing specific indicators for overuse, misuse, and unwarranted variation; Innovative Strategies: Pilot and scale effective strategies for reducing low-value care across diverse European settings, ensuring these solutions are transferable across different healthcare systems; Systems Analysis: Examine healthcare payment and financing models to determine if they unintentionally incentivize low-value care and evaluate alternative models that align with high-value patient outcomes; and Technological Integration: Utilize data models, digital tools, and artificial intelligence to identify inefficiencies and facilitate collaboration between international health registries and databases.
Call for proposals to conduct a comprehensive review of cardiovascular research and innovative healthcare solutions at national, EU, and international levels.
European Union
Call for proposals to conduct a comprehensive review of cardiovascular research and innovative healthcare solutions at national, EU, and international levels. With a total funding allocation of €1.90 million, this initiative aims to identify critical gaps in the field and establish a Strategic Research and Innovation Agenda (SRIA) to improve risk prediction, early detection, and screening for cardiovascular diseases (CVDs) and associated comorbidities like obesity and diabetes. Cardiovascular diseases currently represent the leading cause of death in the EU, accounting for over 1.7 million deaths annually and consuming approximately 11% of healthcare budgets, totaling €282 billion. The proposal is designed to support the upcoming EU Cardiovascular Health plan by integrating digital tools, Virtual Human Twins (VHT), and AI-driven methods. Key activities include: Gap Analysis and Mapping: Conducting a global review of research and innovation, with specific emphasis on addressing sex- and gender-related gaps in diagnosis and treatment; Overcoming Barriers: Generating a detailed report on the obstacles to personalized prevention and providing evidence-based recommendations to bypass these challenges; Inclusive Research Design: Integrating variables such as age, genetic predisposition, lifestyle, and racial or ethnic origin into data analysis to ensure findings are generalizable across diverse populations; Stakeholder Collaboration: Organizing multi-sectoral events to align healthcare providers, researchers, and policymakers, while involving Social Sciences and Humanities (SSH) experts to enhance societal impact.
Call for proposals to support the Public Procurement of Innovative Solutions (PPI) within European health systems.
European Union
Call for proposals to support the Public Procurement of Innovative Solutions (PPI) within European health systems. With a total budget of €24.50 million and individual awards ranging from €3.00 to €8.00 million, the initiative aims to bridge the gap between clinical needs and market-ready innovations. Unlike traditional research grants, this funding specifically targets consortia of procurers—such as hospitals and health authorities—to deploy solutions that facilitate the integration and coordination of care, ultimately making healthcare more personalized, accessible, and inclusive. Proposals must center on the deployment of organizational or technological innovations, such as Artificial Intelligence (AI) for hospital-to-home care coordination or advanced diagnostic tools for personalized medicine. The call prioritizes several vulnerable and high-need groups, including: Vulnerable Patients: Children, the elderly, and frail individuals with complex social and health needs; Chronic & Complex Conditions: People living with multi-morbidities, cancer, rare diseases, or concurrent physical and mental health conditions: and Inclusive Design: Applicants must account for gender and intersectional factors, such as caregiving responsibilities and socioeconomic health disparities, to ensure equitable access.
Call for proposals to modernize the regulatory science governing health technologies within the EU.
European Union
Call for proposals to modernize the regulatory science governing health technologies within the EU. With a total budget of €19.60 million and awards ranging from €4.00 to €6.00 million, the initiative focuses on updating methodologies for clinical evaluation and regulatory assessment. The goal is to ensure that legal frameworks keep pace with rapid innovation in areas such as artificial intelligence (AI), virtual human twins, and new approach methodologies (NAMs), while maintaining rigorous safety and performance standards. Proposals should target the improvement of existing methodologies or explore how novel information sources can provide satisfactory evidence for regulatory needs. Key focus areas include: Refining Evidence Requirements: Closing gaps in clinical evidence clarity and sufficiency for medical devices, in-vitro diagnostics, and substances of human origin (SoHO); Integrating Digital & Bio-medical Approaches: Examining how AI-enabled models, Real-World Data (RWD), and disease-relevant biophysical data can support clinical investigations and predict biological parameters; Optimizing Study Design: Using existing data to improve the planning of first-in-human studies, thereby enhancing participant safety and rationalizing resource use; and Special Populations & Unmet Needs: Exploring regulatory pathways, such as regulatory sandboxes, to accelerate the uptake of technologies for rare diseases and pediatric conditions.
Call for proposals to develop advanced Virtual Human Twins (VHTs).
European Union
Call for proposals to develop advanced Virtual Human Twins (VHTs). With a total budget of €35.00 million, this initiative aims to create dynamic, multiscale digital representations of individuals to better understand cancer onset and progression. These in-silico models are intended to revolutionize personalized medicine by allowing clinicians to simulate and select the most effective intervention options at various anatomical levels, from cellular molecular profiles to entire organ systems. The Commission expects to fund approximately four projects, with individual awards ranging between €8.00 and €9.00 million. Key activities include: Multiscale Modeling: Developing VHTs that integrate FAIR (Findable, Accessible, Interoperable, Reusable) data, including multi-omics, medical imaging, and real-world clinical data, while utilizing AR/VR for model visualization; Validation & Clinical Uptake: Updating and validating these models with longitudinal patient data to demonstrate their usability and capacity to deliver clinically meaningful observations in real-world treatment settings; Open Science & Infrastructure: Making all data and model assets available through the UNCAN.eu and the Advanced VHT Platform. Newly collected datasets must be recorded in the European Health Data Space (EHDS) catalogue; and Multidisciplinary Collaboration: Ensuring active cooperation between AI experts, healthcare professionals, and patients throughout the development process to ensure the models reflect human diversity, including age, sex, and gender.
Call for proposals to address the dual challenge of the healthcare sector’s environmental footprint and its vulnerability to climate change.
European Union
Call for proposals to address the dual challenge of the healthcare sector’s environmental footprint and its vulnerability to climate change. With a total budget of €45.00 million, this initiative seeks to develop and pilot inclusive, accessible interventions that reduce health vulnerabilities while simultaneously greening healthcare operations. As the health sector is responsible for nearly 5% of global greenhouse gas emissions, this call prioritizes the development of low-carbon medical technologies and evidence-based frameworks to quantify the health co-benefits of climate mitigation. The Commission intends to award several grants, with individual projects receiving between €7.00 and €8.00 million. Applicants are expected to focus on scalable and transferable solutions that can be applied across diverse regional and socio-economic contexts. Key activities include: Intervention Piloting: Developing tools to address climate-related health outcomes and reducing the vulnerability of healthcare infrastructures and supply chains; Decarbonization Technologies: Creating low-carbon medical devices and digital solutions to minimize the emission of pollutants into air, water, and soil; Methodology Development: Designing harmonized frameworks and metrics to assess the cost-benefit ratio of climate adaptation versus mitigation strategies in the health sector; and Community Preparedness: Exploring the role of primary care and lifestyle practices in increasing the resilience of individuals and local communities to environmental stressors.
Call for proposals to bolster the competitiveness of the EU biotechnology sector by advancing “closer-to-deployment” health innovations.
European Union
Call for proposals to bolster the competitiveness of the EU biotechnology sector by advancing closer-to-deployment health innovations. With a total budget of €29.50 million, this initiative specifically targets the field of regenerative medicine, providing follow-on funding for promising research previously supported by EU R&I actions. The goal is to bridge the gap between early-stage research and market readiness, accelerating the delivery of life-changing therapies to patients. The call seeks to fund high-impact projects with substantial awards to ensure innovations reach clinical or industrial maturity. Award Range: Between €6.00 and €8.00 million per project. To be successful, proposals must demonstrate a clear pathway from previous EU-funded success to future healthcare impact.
Call for proposals to fund research and innovation actions (RIAs) focused on advancing healthcare through digitalization and data exchange January 28, 2026; Horizon Europe funding opportunities ; Health Grants , Innovation grants , Research grants This initiative provides up to €43.
European Union
This initiative provides up to €43.3 million to fund pre-competitive research and innovation focused on novel tools and technologies that improve the prevention, diagnosis, treatment, and management of diseases. The call specifically targets the digital transformation of healthcare by exploiting the full potential of data exchange and digitalisation. Proposals must address an unmet public health need, such as diseases with a high patient burden or significant economic impact. Key focus areas include: Demonstrating how research can be translated into innovative solutions that fit into Europe’s fragmented healthcare systems; Leveraging advanced analytics and artificial intelligence to improve diagnostic accuracy, shorten time-to-market, and provide personalized health interventions; Ensuring that health technologies account for demographic trends and the real-life challenges of patients with complex chronic diseases. Selected projects are expected to contribute to the EU’s Life Sciences Strategy by strengthening the competitiveness of the European health industry and fostering technological leadership.
Call for nominations to endow the prestigious Frontiers of Knowledge Awards, which recognize world-class research and artistic creation of singular impact.
European Union
Call for nominations to endow the prestigious Frontiers of Knowledge Awards, which recognize world-class research and artistic creation of singular impact. Now in their nineteenth edition, these awards honor fundamental advances that expand the boundaries of human knowledge or represent the emergence of new interdisciplinary fields. Each of the eight award categories—spanning Basic Sciences, Biology and Biomedicine, ICT, Climate Change, Economics, Humanities, Social Sciences, and Music and Opera.
Call for proposals to support pre-competitive research and innovation in the health sector.
European Union
Call for proposals to support pre-competitive research and innovation in the health sector. This initiative seeks to foster the development of safe, effective, and affordable health innovations that address unmet public health needs, ranging from disease prevention and precision diagnostics to chronic disease management. Projects are expected to contribute to the IHI JU Strategic Research and Innovation Agenda by improving the understanding of health determinants and enhancing the competitiveness of the EU health industry. Furthermore, applicants are encouraged to incorporate digital solutions like AI, consider regulatory strategies for timely implementation, and provide open access to research outputs to benefit the wider healthcare community. The Call offers awards of up to EUR 30,000,000.
Call for proposals to fund pre-competitive research and innovation aimed at developing tools and technologies that improve the entire care spectrum, from disease prevention to recovery.
European Union
Call for proposals to fund pre-competitive research aimed at developing novel tools, methods, and technologies that improve the entire spectrum of healthcare, from disease prevention to recovery. This initiative specifically targets IHI JU’s Specific Objective 5, which focuses on creating improved methodologies for assessing the added value of integrated healthcare solutions. Applicants must form a collaborative public-private partnership consortium consisting of at least three independent legal entities from different Member States or Associated Countries. Proposals are expected to address significant unmet public health needs, such as high-burden diseases or high-impact economic challenges, while ensuring that the resulting innovations are patient-centric and capable of being integrated into fragmented European healthcare systems. Key activities should include demonstration pilots that accelerate the discovery and deployment of evidence-based practices, potentially utilizing digitalization and AI to enhance precision diagnostics and personalized medicine. Furthermore, projects must include a regulatory strategy to engage with bodies like the European Medicines Agency (EMA) and national competent authorities to ensure that new, cost-effective solutions can reach the market and patients more efficiently.